Mock Y-90 glass sphere standardization for nuclear medicine applications

Autre titre	Mock Yttrium-90 glass sphere standardization for nuclear medicine applications
Téléchargement	Voir la version finale : Mock Y-90 glass sphere standardization for nuclear medicine applications (PDF, 439 Kio)
DOI	Trouver le DOI : https://doi.org/10.4224/40004093
Auteur	Rechercher : Galea, Raphael¹Identifiant ORCID : https://orcid.org/0000-0003-1639-3788; Rechercher : Moore, Kimberly¹
Affiliation	Conseil national de recherches Canada. Centre de recherche en métrologie
Format	Texte, Rapport technique
Description physique	8 p.
Sujet	glass microspheres; Y-90 microspheres; Yttrium-90; mock standard; nuclear medicine; radionuclide metrology
Résumé	Reliable activity measurements of Yttrium-90 (Y-90) microspheres are critical for quantitative dosimetry and patient safety in liver radioembolization. Recent multicentre studies have identified systematic discrepancies between vendor-stated and independently measured Y-90 activities for both glass and resin microspheres, suggesting inconsistencies in calibration traceability across institutions. The NRC developed a mock glass microsphere standard designed to replicate the geometry and composition of clinical sources to address these metrological challenges. This paper summarizes the background of observed discrepancies, outlines the NRC approach for mock standard development and discusses implications for future standardization efforts.
Date de publication	2026-08-24
Maison d’édition	National Research Council Canada
Langue	anglais
Publications évaluées par des pairs	Non
Identificateur	PIRS-4571
Exporter la notice	Exporter en format RIS
Signaler une correction	Signaler une correction (s'ouvre dans un nouvel onglet)
Identificateur de l’enregistrement	fd51c064-074f-457a-82f0-10afd0f83161
Enregistrement créé	2026-08-19
Enregistrement modifié	2026-08-24

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Conseil national de recherches Canada

Date de modification :: 2026-09-13