| DOI | Trouver le DOI : https://doi.org/10.1016/S0924-2031(01)00150-3 |
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| Auteur | Rechercher : Low-Ying, Sarah1; Rechercher : Shaw, R. Anthony1; Rechercher : Leroux, Michael; Rechercher : Mantsch, Henry H.1 |
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| Affiliation | - Conseil national de recherches Canada. Institut du biodiagnostic du CNRC
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| Format | Texte, Article |
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| Sujet | Blood analysis; Infrared spectroscopy; PLS; Whole blood; Glucose; Urea; Clinical analysis |
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| Résumé | This paper reports the results of a study to determine whether mid-infrared (IR) spectroscopy might form the basis for quantitation of glucose and urea levels in whole blood. Spectra were acquired by first diluting whole blood specimens with a dilute potassium thiocyanate solution, drying small aliquots to dry films on BaF2 substrates and acquiring transmission spectra for the dry films. Reference analyses for urea and glucose were carried out, and partial least-squares calibrations developed using two-thirds of the 200 total specimens for calibration and the remaining one-third to validate the analytical methods. A potassium thiocyanate absorption at 2060 cm−1 provided the means to normalize the spectra, factoring out any minor variations in film thickness. |
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| Date de publication | 2002-02-28 |
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| Dans | |
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| Publications évaluées par des pairs | Oui |
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| Numéro du CNRC | 1907 |
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| Numéro NPARC | 9148546 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | ef0ee926-bc18-47a3-8193-97d4e223ae13 |
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| Enregistrement créé | 2009-06-25 |
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| Enregistrement modifié | 2020-03-30 |
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