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| DOI | Trouver le DOI : https://doi.org/10.1002/ejic.202400077 |
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| Auteur | Rechercher : Chagunda, Ian C.1Identifiant ORCID : https://orcid.org/0000-0003-0578-9701; Rechercher : Williams, Peter J. H.1Identifiant ORCID : https://orcid.org/0000-0001-5148-5587; Rechercher : Fisher, Tiago1; Rechercher : Stock, Naomi L.2Identifiant ORCID : https://orcid.org/0000-0002-3472-9284; Rechercher : Beach, Daniel G.3Identifiant ORCID : https://orcid.org/0000-0002-5680-2112; Rechercher : Thomas, Gilian T.4Identifiant ORCID : https://orcid.org/0000-0002-1468-2714; Rechercher : Zhu, Jane5; Rechercher : McIndoe, J. Scott1Identifiant ORCID : https://orcid.org/0000-0001-7073-5246 |
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| Affiliation | - University of Victoria. Department of Chemistry
- Trent University
- Conseil national de recherches Canada. Centre de recherche en métrologie
- University of Ottawa. Department of Chemistry and Biomolecular Sciences
- University of British Columbia. Department of Chemistry
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| Bailleur de fonds | Rechercher : Institute of Coal Chemistry; Rechercher : Natural Sciences and Engineering Research Council of Canada; Rechercher : Universities Space Research Association; Rechercher : University of Victoria; Rechercher : Trent University |
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| Format | Texte, Article |
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| Sujet | coordination complexes; electrospray ionization; instrument optimization; ion fragmentation; mass spectrometry |
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| Résumé | Electrospray ionization mass spectrometry (ESI-MS) is a powerful tool for identifying and characterizing organometallic and coordination compounds. However, detection of fragile structures bound by weaker intermolecular forces can be significantly limited in ESI-MS owing to the use of relatively harsh instrument conditions and configurations. In this study, a set of tests was developed to assess the softness of ESI-MS systems. Two variants are presented: positive ion mode, utilizing a mixture of sodium ions and triphenylphosphine oxide producing [Na(OPPh₃)n]⁺ ions (n=1–4), and negative ion mode utilizing Pd(PPh₃)₄ and sulfonated triphenylphosphine producing [Pd(L)(PPh₃)n]⁻ ions (n=0–2), where softer instrument conditions preserve a higher proportion of the high-coordinate ions and harsher conditions will result in increased detection of products of ion fragmentation. The results revealed notable variations in instrument softness, which were influenced by a combination of instrument design and experimental parameters. Meticulously optimizing experimental conditions and ESI-MS parameters is essential to achieving the softest ionization possible, ensuring reliable analysis where applicable. This study offers valuable insight through straightforward tests that can be employed to assess the suitability of an instrument for specific research needs. |
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| Date de publication | 2024-05-02 |
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| Maison d’édition | Wiley |
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| Licence | |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | d5a1b424-2eb3-435f-9348-080314ed5907 |
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| Enregistrement créé | 2024-09-11 |
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| Enregistrement modifié | 2024-09-11 |
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