Drosophila innate immunity and response to fungal infections

DOI	Trouver le DOI : https://doi.org/10.1111/j.1462-5822.2008.01120.x
Auteur	Rechercher : Levitin, Anastasia; Rechercher : Whiteway, Malcolm¹
Affiliation	Conseil national de recherches Canada. Institut de recherche en biotechnologie du CNRC
Format	Texte, Article
Sujet	Adult; Cell Line; Drosophila; Drosophila melanogaster; genetics; pharmaceutical
Résumé	The fruit fly Drosophila melanogaster is an important model for the analysis of the interaction between host immune systems and fungal pathogens. Recent experiments have extended our understanding of the Toll-based signalling pathway critical to response to fungal infections, and identified new elements involved in cellular and humoral-based defences. The fly immune system shows remarkable sophistication in its ability to discriminate among pathogens, and the powerful genetics available to researchers studying the adult fly response, and the ability to manipulate cultured phagocytic cell lines with RNAi, are allowing researchers to dissect the molecular details of the process
Date de publication	2008
Langue	anglais
Numéro du CNRC	49547
Numéro NPARC	3538893
Exporter la notice	Exporter en format RIS
Signaler une correction	Signaler une correction (s'ouvre dans un nouvel onglet)
Identificateur de l’enregistrement	be1ff259-05dd-44d2-96d4-b9ee9aca97c4
Enregistrement créé	2009-03-01
Enregistrement modifié	2020-04-15

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