Do physiological and pathological stresses produce different changes in heart rate variability?

Par Conseil national de recherches du Canada

DOI	Trouver le DOI : https://doi.org/10.3389/fphys.2013.00197
Auteur	Rechercher : Bravi, Andrea; Rechercher : Green, Geoffrey; Rechercher : Herry, Christophe; Rechercher : Wright, Heather E.; Rechercher : Longtin, André; Rechercher : Kenny, Glen P.; Rechercher : Seely, Andrew J. E.
Format	Texte, Article
Description physique	8 p.
Sujet	dimensions of variability; disease; domains of variability; exercise; physical activity; sepsis
Résumé	Although physiological (e.g., exercise) and pathological (e.g., infection) stress affecting the cardiovascular system have both been documented to be associated with a reduction in overall heart rate variability (HRV), it remains unclear if loss of HRV is ubiquitously similar across different domains of variability analysis or if distinct patterns of altered HRV exist depending on the stressor. Using Continuous Individualized Multiorgan Variability Analysis (CIMVA™) software, heart rate (HR) and four selected measures of variability were measured over time (windowed analysis) from two datasets, a set (n = 13) of patients who developed systemic infection (i.e., sepsis) after bone marrow transplant (BMT), and a matched set of healthy subjects undergoing physical exercise under controlled conditions. HR and the four HRV measures showed similar trends in both sepsis and exercise. The comparison through Wilcoxon sign-rank test of the levels of variability at baseline and during the stress (i.e., exercise or after days of sepsis development) showed similar changes, except for LF/HF, ratio of power at low (LF) and high (HF) frequencies (associated with sympathovagal modulation), which was affected by exercise but did not show any change during sepsis. Furthermore, HRV measures during sepsis showed a lower level of correlation with each other, as compared to HRV during exercise. In conclusion, this exploratory study highlights similar responses during both exercise and infection, with differences in terms of correlation and inter-subject fluctuations, whose physiologic significance merits further investigation.
Date de publication	2013-07-30
Maison d’édition	Frontiers Media
Dans	Frontiers in Physiology 4.
Langue	anglais
Publications évaluées par des pairs	Oui
Publication du CNRC	Cette publication n’est pas du CNRC Ce sont des publications qui ont été rédigées par un auteur du CNRC, mais avant que celui-ci soit employé du CNRC.
Numéro NPARC	23001153
Exporter la notice	Exporter en format RIS
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Identificateur de l’enregistrement	87f35dfc-659d-4852-befc-4af182b6570a
Enregistrement créé	2016-12-16
Enregistrement modifié	2020-04-22

Date de modification :: 2024-12-26