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| DOI | Trouver le DOI : https://doi.org/10.1016/j.impact.2026.100623 |
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| Auteur | Rechercher : Hermabessiere, Ludovic1Identifiant ORCID : https://orcid.org/0000-0002-6775-2480; Rechercher : Levesque, Bailey1; Rechercher : Chilvers, Violet1; Rechercher : Tom, Justin1; Rechercher : Hui, Joseph P.M.1Identifiant ORCID : https://orcid.org/0009-0002-3241-012X; Rechercher : Vogt, Anja1; Rechercher : Ellis, Lee D.1 |
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| Affiliation | - Conseil national de recherches Canada. Développement des cultures et des ressources aquatiques
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| Bailleur de fonds | Rechercher : National Research Council Canada |
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| Format | Texte, Article |
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| Sujet | fluoxetine; tetrabromobisphenol a; triphenyl phosphate; phenotype; effect concentration |
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| Résumé | Micro and nanoplastics are ubiquitous and can lead to adverse biological effects in exposed organisms. Organisms can also be co-exposed to plastics along with synthetic chemicals. In this work, using the NRC Zebrafish Embryo Toxicity test, we evaluated the potential toxicity of different sized plastic particles, along with the effects of combining them with the known toxicants, triphenyl phosphate, tetrabromobisphenol A and fluoxetine. Following chemical/plastic exposure, morphological abnormalities and behaviour were recorded, along with the chemical uptake of the toxicants by the larvae. The PS sphere particles used (0.42, 2.25 and 8.87 μm) exhibited no significant effects on larvae at the environmental concentrations tested (0.05–50 μg/mL) including no changes in larval behavioural activities. However, the presence of the micro/nanoplastic particles did increase the overt toxicity of the chemicals by changing their EC₅₀. Additionally, for all three chemicals, some plastic sizes decreased larval behaviour during the baseline or first light-dark period. Plastic particles did not modify the chemical uptake by the larvae. This suggests that enhanced toxicity caused by the plastics is not linked to changes in chemical uptake, metabolism, or excretion as hypothesized. Additional studies are necessary to better understand the role of plastic particles in a multiple stressor environment. |
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| Date de publication | 2026-04-01 |
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| Maison d’édition | Elsevier B.V. |
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| Déclaration de droit d’auteur | - Crown Copyright © 2026 Published by Elsevier B.V.
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| Licence | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 7370ad12-0bae-44d6-ae7e-d5fa9fac3349 |
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| Enregistrement créé | 2026-05-19 |
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| Enregistrement modifié | 2026-05-25 |
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