| Auteur | Rechercher : Kogan, G.; Rechercher : Brisson, J.; Rechercher : Kasper, D.; Rechercher : Von Hunolstein, C.; Rechercher : Orefici, G.; Rechercher : Jennings, Harold |
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| Format | Texte, Article |
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| Sujet | 13C; 13C-NMR; 1D; 1H; 2D; Acetylglucosamine; acid; bacterial; bacterial capsules; Canada; capsular polysaccharide; capsule; carbohydrate conformation; carbohydrate sequence; chemistry; d-glucose; elucidation; galactose; glucose; group B streptococcus; group-B; high-resolution; magnetic resonance spectroscopy; molar; molecular sequence data; N-acetylneuraminic acid; NMR; NMR spectroscopy; polysaccharide; repeating unit; repetitive sequences, nucleic acid; resolution; resolution NMR spectroscopy; sialic; sialic acids; spectroscopy; strain; streptococcus; streptococcus agalactiae; structural elucidation; unit |
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| Résumé | The type VII capsular polysaccharide isolated from the newly discovered group B Streptococcus (GBS) strain contains D-glucose, D-galactose, N-acetyl-D-glucosamine and N-acetylneuraminic acid in the molar ratio 2:2:1:1. High-resolution one- and two-dimensional (1D and 2D) 1H and 13C NMR spectroscopy of the native and desialylated polysaccharides showed the type VII GBS capsular polysaccharide to contain the following branched hexasaccharide repeating unit: [formula: see text] Despite extensive structural similarity with the previously described GBS polysaccharides, the type VII polysaccharide showed no cross-reaction with the heterologous antisera |
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| Date de publication | 1995-11-07 |
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| Dans | |
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| Langue | anglais |
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| Numéro du CNRC | KOGAN1995 |
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| Numéro NPARC | 9361350 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 43d22159-9357-4aab-9495-dc7186dd1b10 |
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| Enregistrement créé | 2009-07-10 |
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| Enregistrement modifié | 2020-04-29 |
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