Method Completeness_mean Purity_mean Completeness_std Purity_std 2 – L1 norm error_mean 16 – Weighted UniFrac error_mean L1 norm error_std Weighted UniFrac error_std Dataset Rank Bracken 2.2 95.5976311028575 42.3847835922537 0.703369290570078 6.21309103016673 1.626057 12.7943578836747 0.01939381977733 0.08298985472864 Marine genus CCMetagen 1.1.3 36.8662787634809 87.1874221737901 2.59015994637132 2.23173855017373 1.184441046 10.4996966110161 0.030925633459881 0.117032831544051 Marine genus Centrifuge 1.0.4 beta 92.8996791153071 80.1119206351889 0.96785106939217 3.43737437380734 1.634388 12.7447885360776 0.018228951819686 0.095643140199232 Marine genus DUDes 0.08 43.0909214072619 97.6304269358445 2.54839968189635 1.0348938234964 1.57867634 12.83432155 0.021050989630905 0.127653987589619 Marine genus DUDes cami1 70.6395066338288 66.5728643806771 1.28146055312079 3.18824424278924 1.4549742 11.55237203 0.094089493387862 0.436327301253153 Marine genus FOCUS 1.5 35.1467438347442 44.0117014913037 1.79840333051543 3.34644350628678 0.995203610793725 9.65242974777965 0.037092573277552 0.109712536344793 Marine genus FOCUS cami1 41.0065244811515 36.4693371588579 2.33039818890753 1.97518611918724 1.13941211 9.93471649747043 0.035277625051877 0.091845090126632 Marine genus LSHVec gsa 55.719557195572 91.5151515151515 1.05003734131465 10.1296326899901 Marine genus MetaPalette 1.0.0 24.6680088181281 95.43404098142 8.05954120788852 2.23276436838275 1.11873969586145 10.2672926948466 0.156710573234632 0.398103439528592 Marine genus MetaPhlAn 2.9.22 89.7519395411411 96.1507414651648 0.934590592370772 0.913281416060724 1.68193103 13.31022946 0.03625323501081 0.183983227855517 Marine genus MetaPhlAn cami1 70.9922377702812 97.1818368659732 1.68104801467438 1.36568631957871 1.49948787 11.8106766562425 0.072263382889647 0.34610349613939 Marine genus MetaPhyler 1.25 29.9425853292149 73.7178992263998 2.30295832059083 2.07281432655683 1.231614 10.638919263228 0.032694151090915 0.169115740090262 Marine genus Metalign 0.6.2 avg 77.859778597786 93.3628318584071 1.6265116 11.7830957027556 Marine genus NBC++ 83.6062192124777 15.8609411016652 1.20662316879586 1.34911791410537 1.21587626244406 10.8303503685111 0.038463615946128 0.198433052177327 Marine genus TIPP 4.3.10 56.7368714109453 23.109756097561 1.66886370928654 1.61766713755571 0.987757999999998 10.0220511736736 0.139716822322869 0.660246867969519 Marine genus TIPP cami1 59.1327086394564 24.4584235135094 1.12847012915722 1.79551945546137 1.18576277 11.1688492729534 0.044177464907112 0.142313676299569 Marine genus mOTUs 2.5.1_2 96.5451267268319 95.8466344298493 0.509492049358291 0.817444798226616 1.86693691796256 14.1418826747786 0.019047065760167 0.137866131050772 Marine genus mOTUs cami1 63.968992766721 78.3793791495948 1.67323437762782 4.32522390492735 1.141410981 10.2368565357926 0.072203355855425 0.338119301913928 Marine genus Bracken 2.2 100 12.1158190073679 0 2.81758355004064 1.53819246 12.2783538608359 0.052630904969874 0.266730340967863 Strain-madness genus CCMetagen 1.1.3 60.8333333333333 37.0370342788932 8.24872877326317 5.11535222837596 1.3989038233 12.0548320222986 0.167042968436354 0.999315807138514 Strain-madness genus Centrifuge 1.0.4 beta 96.6666666666667 23.8891017479802 4.1030496993111 3.31923458164506 1.68224982 13.0035146741601 0.047743243247876 0.265695745138216 Strain-madness genus DUDes 0.08 60.1666666666667 95.3209956709957 7.63762615825973 6.07960661661353 1.332580347 11.013581146 0.140079041779897 0.790715400869512 Strain-madness genus DUDes cami1 91.75 57.8481690086062 6.32266956220369 5.77825420080124 1.692817301 12.495702645 0.082548393726644 0.457755228547261 Strain-madness genus FOCUS 1.5 67.4166666666667 15.0399435250212 9.91652873174591 2.17442786922543 1.33325413752799 10.4006031961983 0.062135443673593 0.316542665043783 Strain-madness genus FOCUS cami1 74.5 12.0187481245908 8.92825877278458 1.33998072742768 1.375151866 10.4712814605201 0.066936026113806 0.30995424554775 Strain-madness genus LSHVec gsa 33.3333333333333 100 1.72070547800987 13.5308625104653 Strain-madness genus MetaPhlAn 2.9.22 89.1666666666667 92.8257575757576 4.01666003045122 3.16221716300146 1.875000339 14.285225307 0.041820848378194 0.199116185039893 Strain-madness genus MetaPhlAn cami1 71.5833333333333 91.1475468975469 7.11606125055575 4.86882674322194 1.71698778 13.5859427895108 0.101259384033869 0.237096411112207 Strain-madness genus MetaPhyler 1.25 92.25 79.1703553799142 5.46067977169725 7.24577112124531 1.60842714 13.4464988538971 0.088643196537377 0.193688428344385 Strain-madness genus Metalign 0.6.2 58.3333333333333 63.6363636363636 1.5181987 11.9589158286913 Strain-madness genus TIPP 4.3.10 100 3.84615384615384 0 0 1.43767212 12.1606850764193 0.175078124112504 0.964735123690498 Strain-madness genus TIPP cami1 99.5 4.20903836100178 1.98902713813285 0.279809263771404 1.7741801591 13.9262639514656 0.037336686185993 0.152778495654327 Strain-madness genus mOTUs 2.5.1_6 93.5833333333333 37.2928298439897 4.86273421676023 3.640046890885 1.50763803065373 7.16234408729664 0.137411176956806 1.85807727875623 Strain-madness genus mOTUs cami1 92.9166666666667 69.1333529430666 5.96649361147003 6.48246944011284 1.9049429977 13.5308779237898 0.062553924777468 0.317553272192509 Strain-madness genus