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Single-molecule force spectroscopy on Bombyx mori silk fibroin by atomic force microscopy

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1021/la991230y
AuthorSearch for: ; Search for: ; Search for: ORCID identifier: https://orcid.org/0000-0002-2480-6821; Search for: ; Search for: ; Search for: ; Search for: ; Search for: ; Search for:
FormatText, Article
Abstract
A new atomic force microscopy (AFM)-based technique, single-molecule force spectroscopy (SMFS), was used to study the nanomechanics of Bombyx mori silk fibroin. Three types of force-extension curves were found in the system. A modified freely jointed chain (MFJC) model can fit two of the three types well, but the fit parameters are different. The third type of force curve, in which there exists a plateau, cannot be modeled by MFJC. These results may show that there are three kinds of conformations in the silk fibroin system and SMFS can “distinguish” different conformations of the polymer chains.
Publication date
PublisherAmerican Chemical Society (ACS)
In
  • Langmuir 16, no. 9 (25 March 2000): 4305–4308.
LanguageEnglish
Peer reviewedYes
NRC publication
This is a non-NRC publication

"Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.

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Record identifierfb762e36-446a-4276-b50b-57a9acbf6fe1
Record created2023-04-04
Record modified2023-04-11
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