| DOI | Resolve DOI: https://doi.org/10.1007/978-3-7091-0870-3_17 |
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| Author | Search for: MacKenzie, Roger1; Search for: Müller-Loennies, Sven |
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| Affiliation | - National Research Council of Canada. Human Health Therapeutics
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| Format | Text, Book Chapter |
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| Abstract | Over the past two decades surface plasmon resonance (SPR) has emerged as gold standard technology for the analysis of biomolecular interactions. In the monoclonal antibody (mAb) development area SPR is employed from the early screening stages to detailed characterization of binding kinetics and affinities to epitope mapping to final product testing. This label free technology provides high quality kinetic and affinity data and, in some instances, other unique information not obtained by alternative methods such as ELISA. SPR is well-suited to the study of protein-carbohydrate interactions which are often of low affinity and not easily characterized by other methods. |
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| Publication date | 2011-10-11 |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| NPARC number | 21275592 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | f8fc3930-a093-4628-a8b9-5d649471ac64 |
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| Record created | 2015-07-14 |
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| Record modified | 2020-03-03 |
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