Ex-vivo evaluation of an early caries detector based on integrated OCT and polarized Raman spectroscopy (conference presentation)

From National Research Council Canada

DOI	Resolve DOI: https://doi.org/10.1117/12.2253224
Author	Search for: Lamouche, Guy¹; Search for: Padioleau, Christian¹; Search for: Hewko, Mark²; Search for: Smith, Michael S. D.²; Search for: Schattka, Bernie J.²; Search for: Fulton, Crystal²; Search for: Gauthier, Bruno¹; Search for: Beauchesne, André¹; Search for: Ko, Alex C.²; Search for: Choo-Smith, Lin-P'ing; Search for: Sowa, Michael G.²
Name affiliation	National Research Council Canada. Energy, Mining and Environment National Research Council Canada. Medical Devices
Format	Text
Type	Article
Proceedings title	Lasers in Dentistry XXIII
Series title	Proceedings of SPIE; no. 10044
Conference	SPIE BiOS,2017, Jan. 28-Feb. 2, 2017, San Francisco, CA, USA
ISSN	0277-786X 1996-756X
ISBN	9781510605299 1510605290
Abstract	Early detection of incipient caries would allow dentists to provide more effective measures to delay or to reverse caries’ progression at earlier stage. Such earlier intervention could lead to improved oral health for the patients and reduced burden to the health system. Previously, we have demonstrated that the combination of morphological and biochemical information furnished by optical coherence tomography (OCT) and polarized Raman spectroscopy (PRS), respectively, provided a unique tool for dental caries management. In this study we will report the first pre-clinical caries detection system that includes a hand-held probe with a size slightly larger than a tooth brush. This probe presents a novel platform combining both OCT and PRS optics in a very tight space ideal for clinical practice. OCT cross-sectional images of near-surface enamel morphology are obtained with miniaturized MEMS scanning device and are processed in real-time to identify culprit regions. These regions are sequentially analyzed with polarized Raman spectroscopy for further confirmation. PRS is performed using 830nm laser line and four detection channels in order to obtain polarized Raman spectroscopic data, i.e. depolarization ratio of the hydroxyapatite Raman band at ~960 cm-1. A detailed description of this hand-held caries detector and ex-vivo/in-vivo test results will be presented.
Publication date	2017-04-19
Publisher	Society of Photo-Optical Instrumentation Engineers (SPIE)
Language	English
Peer reviewed	Yes
NPARC number	23002206
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Record identifier	d2f4e2c1-500f-4273-96b5-ecc07d55ba67
Record created	2017-09-05
Record modified	2020-03-16

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Date modified:: 2020-04-10