Electrical activity of artificial ion channels incorporated into planar lipid bilayers

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1039/A701060E
AuthorSearch for: ; Search for: ; Search for:
FormatText, Article
Subjectenvironmental
Abstract
The ion transport ability in a planar lipid bilayer of a 21 amino acid peptide bearing six 21-crown-7 side chains is reported. The compound was designed to form an artificial ion channel by stacking the crown rings, when adopting an á-helical conformation in a bilayer membrane. All the derivatives of 1 exhibited membrane conductivity with the best results obtained with the unprotected analog 4. The latter showed typical single channel activity.
Publication date
In
  • Journal of the Chemical Society, Perkin Transactions 2, no. 8 (1997): 1469–1471.
LanguageEnglish
NRC publication
This is a non-NRC publication

"Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.

NRC number41770
NPARC number3539977
Export citationExport as RIS
Report a correctionReport a correction
Record identifierd0533652-a335-4f9a-b556-16442349996f
Record created2009-03-01
Record modified2020-03-20
Report a problem on this page
Date modified: