Electrical activity of artificial ion channels incorporated into planar lipid bilayers

DOI	Resolve DOI: https://doi.org/10.1039/A701060E
Author	Search for: Voyer, Normand; Search for: Potvin, Léna; Search for: Rousseau, Éric
Format	Text, Article
Subject	environmental
Abstract	The ion transport ability in a planar lipid bilayer of a 21 amino acid peptide bearing six 21-crown-7 side chains is reported. The compound was designed to form an artiﬁcial ion channel by stacking the crown rings, when adopting an á-helical conformation in a bilayer membrane. All the derivatives of 1 exhibited membrane conductivity with the best results obtained with the unprotected analog 4. The latter showed typical single channel activity.
Publication date	1997
In	Journal of the Chemical Society, Perkin Transactions 2, no. 8 (1997): 1469–1471.
Language	English
NRC publication	This is a non-NRC publication "Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.
NRC number	41770
NPARC number	3539977
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Record identifier	d0533652-a335-4f9a-b556-16442349996f
Record created	2009-03-01
Record modified	2020-03-20