National Research Council of Canada. NRC Institute for National Measurement Standards
Photonic applications in biosensing and imaging, 12-14 September 2005, Toronto, Ontario, Canada
Photoluminescent porous Si (pSi) is a potentially attractive material for biosensor devices. Its ease of fabrication, large active surface area and unique optical properties are just some important attributes. Among other transduction techniques, it is possible to monitor the onset of molecular binding events through the effective quenching of the bright pSi photoluminescence. Here we present the study of effective quenching through a colloidal Ag nanoparticle interaction with pSi. Placing the metallic nanoparticles in close proximity to the light emitting pSi can effectively sweep away the charge carriers from the semiconductor surface and result in a carrier depletion region near the Si-nanoparticle interface. By labeling the targeted bio-species with a silver nanoparticle, and the pSi surface with an appropriate receptor molecule ; in-situ PL monitoring can provide a real-time transduction scheme for the pSi- based biosensor devices.
Photonic applications in biosensing and imaging, 596908 (2005): 596908-1–596908-9.