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Silyamandin, a novel flavonolignan isolated from milk thistle tinctures

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1055/s-2007-981595
AuthorSearch for: 1; Search for: 1; Search for: 1; Search for: 1
Affiliation
  1. National Research Council of Canada. NRC Institute for Marine Biosciences
FormatText, Article
Abstract
Our investigations into the stability of tincture preparations of milk thistle fruit [Silybum marianum L. Gaertn. (Asteraceae)] have led to the characterization of a new flavonolignan 4-(4-hydroxy-3-methoxyphenyl)-7-[(2R,3R) -3,5,7-trihydroxy-4-oxochroman-2-yl]-1-oxo-1,3,3a,4,5,7a-hexahydro-2-benzofuran- 5-carboxylic acid called silyamandin (1). Incubation of the tincture at 40 C for 3 months resulted in an increase in the level of this compound, as observed in the LC/DAD silymarin profile.
Publication date
In
  • Planta Medica 73, no. 11 (September 2007): 1214–1216.
LanguageEnglish
Peer reviewedYes
NRC numberNRCC 42686
1256
NPARC number3538278
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Record identifierbf6b057f-177f-44f2-b5a0-91e4db12f0c1
Record created2009-03-01
Record modified2020-05-10
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