| Download | - View accepted manuscript: Advances in radical-trapping antioxidant chemistry in the 21st century: A kinetics and mechanisms perspective (PDF, 1 MB)
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| DOI | Resolve DOI: https://doi.org/10.1021/cr500226n |
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| Author | Search for: Ingold, Keith U.1 ; Search for: Pratt, Derek A. |
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| Name affiliation | - National Research Council Canada. Security and Disruptive Technologies
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| Format | Text |
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| Type | Article |
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| Journal title | Chemical Reviews |
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| ISSN | 0009-2665 |
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| Volume | 114 |
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| Issue | 18 |
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| Pages | 9022–9046; # of pages: 25 |
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| Subject | Industrial research; Structural optimization; 20th century; Anti-oxidant chemistry; Commercial perspectives; Degenerative disease; Kinetics and mechanism; Optimal performance; Radical trapping; Synergistic interaction; Antioxidants |
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| Abstract | Antioxidants were divided in two parts radical-trapping antioxidants (RTAs) and preventive antioxidants. By the final quarter of the 20th century, the commercial importance of antioxidants was overshadowed by their putative role in human health, as the implication of radical-mediated oxidation in virtually all types of degenerative diseases, including cancer and aging, emerged. From a commercial perspective, there continues to be significant interest in the development of RTA technology. Much of the industrial research effort has been on optimization of the structures of existing RTAs to provide appropriate physical properties and identification of combinations of existing RTAs that achieve optimal performance via the synergistic interactions. |
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| Publication date | 2014-09-02 |
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| Publisher | ACS Publishing |
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| Language | English |
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| Peer reviewed | Yes |
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| NPARC number | 21275468 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction |
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Record identifier | be52eb53-3488-492c-8d10-f6d56d0a36e5 | | Record created | 2015-07-14 |
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| Record modified | 2019-03-06 |
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