| Download | - View accepted manuscript: Thermal stability of cannabinoids in dried cannabis: a kinetic study (PDF, 592 KiB)
- View supplementary information: Thermal stability of cannabinoids in dried cannabis: a kinetic study (PDF, 1.3 MiB)
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| DOI | Resolve DOI: https://doi.org/10.1007/s00216-020-03098-2 |
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| Author | Search for: Meija, Juris1ORCID identifier: https://orcid.org/0000-0002-3349-5535; Search for: McRae, Garnet1; Search for: Miles, Christopher O.1; Search for: Melanson, Jeremy E.1 |
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| Affiliation | - National Research Council of Canada. Metrology Research Centre
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| Format | Text, Article |
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| Subject | cannabis; stability of cannabinoids; Bayesian kinetic modeling |
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| Abstract | This study was undertaken to quantitatively explore the effect of temperature on the degradation of cannabinoids in dried cannabis flower. A total of 14 cannabinoids were monitored using liquid chromatography and tandem mass spectrometry in temperature environments from − 20 to + 40 °C lasting up to 1 year. We find that a network of first-order degradation reactions is well-suited to model the observed changes for all cannabinoids. While most studies focus on high-temperature effects on the cannabinoids, this study provides high-precision quantitative assessment of room temperature kinetics with applications to shelf-life predictions and age estimates of cannabis products. |
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| Publication date | 2021-01-08 |
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| Publisher | Springer |
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| In | |
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| Note | Part of ABCs 20th Anniversary Topical Collection |
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| Language | English |
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| Peer reviewed | Yes |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | a52a9bed-57d7-49e7-a6da-652de5b92cb9 |
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| Record created | 2021-04-27 |
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| Record modified | 2023-06-30 |
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