The L-type calcium channel blockers, Hantzsch 1,4-dihydropyridines, are not peroxyl radical-trapping, chain-breaking antioxidants

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DOIResolve DOI: https://doi.org/10.1021/tx0502591
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  1. National Research Council Canada
FormatText
TypeArticle
Journal titleChemical Research in Toxicology
ISSN0893-228X
Volume19
Issue1
Pages7985; # of pages: 7
Subject1,1 diphenyl 2 picrylhydrazyl; 1,4 dihydropyridine; 5,6 dihydroazacitidine; 6 hydroxy 2,2,5,7,8 pentamethylchroman; acridan; acridine derivative; antioxidant; calcium channel blocking agent; calcium channel L type; calcium channel L type blocking agent; chain breaking antioxidant; cumene; dibenzo 1,4 dihydropyridine derivative; dihydropyridine derivative; lacidipine; n deuterio 5,6 dihydroazacitidine; n methyl 5,6 dihydroazacitidine; n methyl 9,10 dihydroacridine; nicardipine; peroxy radical; probucol; styrene; trolox C; unclassified drug; antioxidant activity; article; calcium binding; carbon hydrogen bond dissociation enthalpy; dissociation; enthalpy; hydrogen bond; nonhuman; reaction analysis; reaction optimization; Acridines; Antioxidants; Benzene Derivatives; Biphenyl Compounds; Calcium Channel Blockers; Calcium Channels, L-Type; Chromans; Dihydropyridines; Free Radicals; Hydrazines; Kinetics; Nifedipine; Nimodipine; Oxidation-Reduction; Peroxides; Styrene
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PublisherAmerican Chemical Society
LanguageEnglish
Peer reviewedYes
NPARC number21276484
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Record identifier9843f5c4-91a3-4f76-960a-7a610e0148db
Record created2015-10-13
Record modified2017-03-26
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