DOI | Resolve DOI: https://doi.org/10.1002/anie.201200596 |
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Author | Search for: Nycholat, Corwin M.; Search for: Mcbride, Ryan; Search for: Ekiert, Damian C.; Search for: Xu, Rui; Search for: Rangarajan, Janani; Search for: Peng, Wenjie; Search for: Razi, Nahid; Search for: Gilbert, Michel1; Search for: Wakarchuk, Warren1; Search for: Wilson, Ian A.; Search for: Paulson, James C. |
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Affiliation | - National Research Council of Canada. NRC Institute for Biological Sciences
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Format | Text, Article |
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Subject | glycans; hemagglutinins; influenza viruses; microarrays; sialic acids |
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Abstract | Human influenza viruses are proposed to recognize sialic acids (pink diamonds) on glycans extended with poly-LacNAc chains (LacNAc=(yellow circle+blue square)). N- and O-linked glycans were extended with different poly-LacNAc chains with α2-3- and α2-6-linked sialic acids recognized by human and avian influenza viruses, respectively. The specificity of recombinant hemagglutinins (receptors in green) was investigated by using glycan microarray technology. |
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Publication date | 2012-04-13 |
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In | |
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Language | English |
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Peer reviewed | Yes |
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NPARC number | 21268200 |
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Export citation | Export as RIS |
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Report a correction | Report a correction (opens in a new tab) |
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Record identifier | 870ce9ae-23a5-4616-b4be-8b2979e11e7e |
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Record created | 2013-06-03 |
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Record modified | 2020-04-21 |
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