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Aspartate and glutamate as synaptic transmitters of parallel visual cortical pathways

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1007/BF00235323
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FormatText, Article
Subjectanimals; aspartic acid/physiology; cats; female; glutamates/physiology; glutamic acid; male; synapses/physiology; synaptic transmission; visual cortex/physiology; aspartate; glutamate; lateral suprasylvian cortex; visual pathways; amino acid release
Abstract
Push-pull cannulae were inserted into both medial and lateral banks of the suprasylvian sulcus and used for local perfusion with artificial extracellular fluid (aECF). Electrical stimulations of regions of cortex projecting to the lateral suprasylvian area (LSA) were accompanied by enhanced levels of release of excitatory amino acids. Electrical stimulation of the area 17/18 border evoked a greater release of aspartate relative to glutamate in the medial bank of the LSA (posteromedial lateral suprasylvian: PMLS), of glutamate over aspartate in the lateral bank (posterolateral lateral suprasylvian: PLLS) while in the fundus, both were released equally or glutamate levels were slightly elevated over those of aspartate. These data support and extend the earlier proposition (Hicks and Guedes 1983) that an excitatory amino acid mediates synaptic transmission within visual cortico-cortical pathways.
Publication date
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  • Experimental Brain Research 58, no. 2 (April 1985): 421–425.
LanguageEnglish
Peer reviewedYes
NRC publication
This is a non-NRC publication

"Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.

NRC numberHICKS1985A
NPARC number9381735
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Record identifier83bc4330-05c8-41dc-834b-aa6f0858db74
Record created2009-07-10
Record modified2023-11-01
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