| DOI | Resolve DOI: https://doi.org/10.3109/17435390.2013.778345 |
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| Author | Search for: Ong, K.J.; Search for: Zhao, X.; Search for: Thistle, M.E.; Search for: Maccormack, T.J.; Search for: Clark, R.J.; Search for: Ma, G.; Search for: Martinez-Rubi, Y.1; Search for: Simard, B.1; Search for: Loo, J.S.C.; Search for: Veinot, J.G.C.2; Search for: Goss, G.G.2 |
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| Affiliation | - National Research Council of Canada. Security and Disruptive Technologies
- National Research Council of Canada. National Institute for Nanotechnology
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| Format | Text, Article |
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| Subject | cadmium selenide; nanoparticle; proteinase; silicon derivative; silicon nanoparticle; silver nanoparticle; single walled nanotube; unclassified drug; zinc nanoparticle; zinc oxide; chorion; embryo; embryo development; enzyme activity; enzyme inhibition; hatching; hydrodynamics; morphology; zebra fish; zeta potential |
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| Abstract | Aquatic organisms are susceptible to waterborne nanoparticles (NP) and there is only limited understanding of the mechanisms by which these emerging contaminants may affect biological processes. This study used silicon (nSi), cadmium selenide (nCdSe), silver (nAg) and zinc NPs (nZnO) as well as single-walled carbon nanotubes (SWCNT) to assess NP effects on zebrafish (Danio rerio) hatch. Exposure of 10 mg/L nAg and nCdSe delayed zebrafish hatch and 100 mg/L of nCdSe as well as 10 and 100 mg/L of uncoated nZnO completely inhibited hatch and the embryos died within the chorion. Both the morphology and the movement of the embryos were not affected, and it was determined that the main mechanism of hatch inhibition by NPs is likely through the interaction of NPs with the zebrafish hatching enzyme. Furthermore, it was concluded that the observed effects arose from the NPs themselves and not their dissolved metal components. © 2014 Informa UK, Ltd. |
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| Publication date | 2014 |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| NPARC number | 21270811 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 643ef7a8-7107-483c-b4a2-326edc579bff |
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| Record created | 2014-02-17 |
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| Record modified | 2020-04-22 |
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