Synthesis of a novel radical trapping and carbonyl group trapping anti-AGE agent: A pyridoxamine analogue for inhibiting advanced glycation (AGE) and lipoxidation (ALE) end products

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1021/ol0348147
AuthorSearch for: 1; Search for: 1; Search for: 1
Name affiliation
  1. National Research Council of Canada. NRC Steacie Institute for Molecular Sciences
FormatText, Article
Journal titleOrganic Letters
ISSN1523-7060
Volume5
Issue15
Pages26592662
Subject6 dimethylaminopyridoxamine; drug analog; pyridoxamine; trolox C; unclassified drug; drug activity; drug efficacy; drug structure; drug synthesis; glycation; lipid oxidation; protein cross linking; structure analysis; substitution reaction; antioxidants; cross-linking reagents; free radicals; glycosylation end products, advanced; lipid peroxidation; proteins; pyridoxamine; ribose; spectrometry, fluorescence
Abstract
Publication date
LanguageEnglish
Peer reviewedYes
NPARC number21276488
Export citationExport as RIS
Report a correctionReport a correction
Record identifier62b3802d-a8ae-4f51-a0e5-f33e4657e452
Record created2015-10-13
Record modified2020-04-02
Date modified: