Deficiency of the chromatin regulator Brpf1 causes abnormal brain development

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  1. National Research Council of Canada. Human Health Therapeutics
FormatText, Article
Subjectacetylation; amino acids; chromosomes; gene expression; transcription; acetyl transferase; epigenetic mechanisms; histone acetylation; histone acetyltransferases; intellectual disability; multiple genes; neurological disorders; gene expression regulation; chromatin regulator BRPF1; HBO1 protein; histone acetyltransferase; homeodomain protein; lysine acetyltransferase 6A; lysine acetyltransferase 6B; lysine acetyltransferase 7; MORF protein; MOZ protein; protein; transcription factor; transcription factor Foxa1; transcription factor Lhx4; transcription factor TBX5; transcription factor Twist1; zinc finger protein; agenesis; animal experiment; brain cortex; brain development; brain malformation; corpus callosum; corpus callosum agenesis; epigenetics; forebrain; forebrain development; gene; gene expression; gene mutation; genetic transcription; histone acetylation; Hox gene; in vivo study; intellectual impairment; mouse; nervous system development; neurologic disease; Otx1 gene; Robo3 gene
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PublisherAmerican Society for Biochemistry and Molecular Biology
Peer reviewedYes
NPARC number21275638
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Record identifier60120282-8ce1-494d-805b-b95ee4ab9424
Record created2015-07-14
Record modified2020-04-22
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