| DOI | Resolve DOI: https://doi.org/10.1128/jvi.00509-22 |
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| Author | Search for: Lin, Jonah; Search for: Law, Ryan; Search for: Korosec, Chapin S.; Search for: Zhou, Christine; Search for: Koh, Wan Hon; Search for: Ghaemi, Mohammad Sajjad1; Search for: Samaan, Philip; Search for: Ooi, Hsu Kiang1ORCID identifier: https://orcid.org/0000-0001-7934-4866; Search for: Matveev, Vitaliy; Search for: Yue, FengYun; Search for: Gingras, Anne-Claude; Search for: Estacio, Antonio; Search for: Buchholz, Megan; Search for: Cheatley, Patti Lou; Search for: Mohammadi, Avid; Search for: Kaul, Rupert; Search for: Pavinski, Katerina; Search for: Mubareka, Samira; Search for: McGeer, Allison J.; Search for: Leis, Jerome A.; Search for: Heffernan, Jane M.; Search for: Ostrowski, MarioORCID identifier: https://orcid.org/0000-0002-7369-1936 |
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| Editor | Search for: Heise, Mark T. |
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| Affiliation | - National Research Council Canada. Digital Technologies
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| Funder | Search for: Gouvernement du Canada | Canadian Institutes of Health Research; Search for: Ontario HIV Treatment Network |
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| Format | Text, Article |
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| Subject | ELISpot assay; SARS-CoV-2; T cell immunity; cytokines; granzyme B; immune modeling |
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| Abstract | Our findings highlight the relative importance of SARS-CoV-2-specific GzmB-producing T cell responses in SARS-CoV-2 control and shared CD4 and CD8 immunodominant epitopes in seasonal coronaviruses or SARS-CoV-1, and they indicate robust persistence of T cell memory at least 1 year after infection. Our findings should inform future strategies to induce T cell vaccines against SARS-CoV-2 and other coronaviruses. |
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| Publication date | 2022-06-14 |
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| Publisher | American Society for Microbiology |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 59103c22-1dda-4057-a5c4-ec8f1bb76713 |
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| Record created | 2022-07-11 |
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| Record modified | 2022-10-19 |
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