| Download | - View final version: Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire (PDF, 1.6 MiB)
- View supplementary information: Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire (PDF, 8.8 MiB)
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| DOI | Resolve DOI: https://doi.org/10.1038/s42003-019-0448-9 |
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| Author | Search for: Filman, David J.; Search for: Marino, Stephen F.; Search for: Ward, Joy E.; Search for: Yang, Lu1ORCID identifier: https://orcid.org/0000-0002-6896-8603; Search for: Mester, Zoltán1ORCID identifier: https://orcid.org/0000-0002-2377-2615; Search for: Bullitt, Esther; Search for: Lovley, Derek R.; Search for: Strauss, Mike |
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| Affiliation | - National Research Council Canada. Metrology Research Centre
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| Format | Text, Article |
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| Subject | bioenergetics; cellular microbiology; soil microbiology |
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| Abstract | Electrically conductive pili from Geobacter species, termed bacterial nanowires, are intensely studied for their biological significance and potential in the development of new materials. Using cryo-electron microscopy, we have characterized nanowires from conductive G. sulfurreducens pili preparations that are composed solely of head-to-tail stacked monomers of the six-heme C-type cytochrome OmcS. The unique fold of OmcS — closely wrapped around a continuous stack of hemes that can serve as an uninterrupted path for electron transport — generates a scaffold that supports the unbranched chain of hemes along the central axis of the filament. We present here, at 3.4 Å resolution, the structure of this cytochrome-based filament and discuss its possible role in long-range biological electron transport. |
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| Publication date | 2019-07-19 |
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| Publisher | Nature Research |
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| Licence | |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 433a99b3-3870-4540-bd56-ef867ee480a0 |
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| Record created | 2020-11-23 |
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| Record modified | 2024-08-12 |
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