Abstract | Diarrhetic shellfish poisoning (DSP) is a gastrointestinal illness caused by consumption of shellfish contaminated by certain toxic dinoflagellates. The main agents known to be responsible for the toxic effects are okadaic acid (OA) and the dinophysistoxins, DTX-1 and DTX-2. Until now the only DSP toxin found in Galician samples was okadaic acid. On some occasions, however, mussel samples that tested pos. in the mouse bioassay showed only low levels of OA by liq. chromatog. anal. In these cases, an extra peak was sometimes obsd. in chromatograms close to that of OA. It was suspected that this might have been due to DTX-2. The presence of DTX-2 in 1990 and 1993 Galician mussels samples has now been confirmed by liq. chromatog.-mass spectrometry. |
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