Epicalyxin F and calyxin I : two novel antiproliferative diarylheptanoids from the seeds of Alpinia blepharocalyx

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1021/ol990260p
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FormatText
TypeArticle
Journal titleOrganic Letters
ISSN1523-7060
1523-7052
Volume1
Issue11
Pages1733–1736; # of pages: 4
Abstract
Epicalyxin F (1) and calyxin I (2), two novel diarylheptanoids, were isolated from a residual fraction of an EtOH extract of Alpinia blepharocalyx. Calyxin I (2) represented a new carbon skeleton, and epicalyxin F (1) possessed potent antiproliferative activity toward HT-1080 fibrosarcoma and colon 26-L5 carcinoma with ED50 values of 1.71 and 0.89 μM, respectively.
Publication date
LanguageEnglish
Peer reviewedYes
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NPARC number21275304
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Record identifier2a4665c5-08c8-465c-9eb0-9e430214214d
Record created2015-06-04
Record modified2016-05-09
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