Epicalyxin F and calyxin I : two novel antiproliferative diarylheptanoids from the seeds of Alpinia blepharocalyx

DOI	Resolve DOI: https://doi.org/10.1021/ol990260p
Author	Search for: Gewali, Mohan B.; Search for: Tezuka, Yasuhiro; Search for: Banskota, Arjun H.; Search for: Ali, Mohammad Shawkat; Search for: Saiki, Ikuo; Search for: Dong, Hui; Search for: Kadota, Shigetoshi
Format	Text, Article
Journal title	Organic Letters
ISSN	1523-7060 1523-7052
Volume	1
Issue	11
Pages	1733–1736
Abstract	Epicalyxin F (1) and calyxin I (2), two novel diarylheptanoids, were isolated from a residual fraction of an EtOH extract of Alpinia blepharocalyx. Calyxin I (2) represented a new carbon skeleton, and epicalyxin F (1) possessed potent antiproliferative activity toward HT-1080 fibrosarcoma and colon 26-L5 carcinoma with ED50 values of 1.71 and 0.89 μM, respectively.
Publication date	1999-10-21
Language	English
Peer reviewed	Yes
NRC publication	This is a non-NRC publication "Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.
NPARC number	21275304
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Record identifier	2a4665c5-08c8-465c-9eb0-9e430214214d
Record created	2015-06-04
Record modified	2020-03-20