| DOI | Resolve DOI: https://doi.org/10.1016/j.carres.2017.06.007 |
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| Author | Search for: Vinogradov, Evgeny1; Search for: Michael, Frank St.1; Search for: Cox, Andrew D.1 |
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| Affiliation | - National Research Council of Canada. Human Health Therapeutics
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| Format | Text, Article |
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| Subject | Fusobacterium nucleatum; lipopolysaccharide; NMR spectroscopy; polysaccharide structure |
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| Abstract | Fusobacterium nucleatum is an anaerobic bacterium found in the human mouth where it causes periodontitis. It was also found in colorectal cancer tissues and is linked with pregnancy complications, including pre-term and still births. Cell surface structures of the bacterium could be implicated in pathogenesis. Here we report the following structure of the lipopolysaccharide O-chain of F. nucleatum strain 12230: -6-α-d-Glc-4-β-d-GlcNHBu3NHBuA-3-β-d-QuiNAc4NABu- where ABu and HBu indicate (R)-3-aminobutanoyl and (R)-3-hydroxybutanoyl, respectively; all monosaccharides are in the pyranose form. |
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| Publication date | 2017-06-16 |
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| Publisher | Elsevier |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| NPARC number | 23002270 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 228149ac-c50c-4901-8086-6ebfb341f158 |
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| Record created | 2017-09-27 |
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| Record modified | 2020-03-16 |
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