| DOI | Resolve DOI: https://doi.org/10.1016/0005-2736(86)90501-8 |
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| Author | Search for: Burton, G.W.1; Search for: Cheng, S.C.1; Search for: Webb, A.1; Search for: Ingold, K. U.1 |
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| Affiliation | - National Research Council of Canada
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| Format | Text, Article |
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| Subject | α-Tocopherol; vitamin E; arachidonic acid; aging; (Human erythrocyte) |
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| Abstract | Young and old human red blood cells contain about the same amount of α-tocopherol, a compound which has previously been shown to be the major lipid-soluble, chain-breaking antioxidant present in such cells. Since red blood cells lose up to ca. 20% of lipid material from their membrane as they age, the α-tocopherol/ membrane-lipid ratio actually rises with age rather than declining as might have been expected on the basis of the free radical theory of aging. The α-tocopherol/arachidonic acid moiety ratios increase in the order: young red blood cells /lt; old red blood cells /lt; plasma, which argues against the suggested membrane 177 stabilizing effect of α-tocopherol/arachidonic acid moiety complexes. |
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| Publication date | 1986 |
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| Publisher | Elsevier |
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| In | |
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| Note | The authors were affiliated with the National Research Council of Canada, Division of Chemistry when they authored this article. |
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| Language | English |
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| Peer reviewed | Yes |
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| NRC number | NRCC 25977 |
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| NPARC number | 21276716 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 1a39cda9-a5bb-49d2-bf94-41468e716c44 |
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| Record created | 2015-10-13 |
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| Record modified | 2020-03-17 |
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