| DOI | Resolve DOI: https://doi.org/10.1101/gad.13.13.1678 |
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| Author | Search for: Gray, William M.; Search for: del Pozo, J. Carlos; Search for: Walker, L.; Search for: Hobbie, Loni; Search for: Risseeuw, Eddy1; Search for: Banks, Travis1; Search for: Crosby, William L.1; Search for: Yang, Ming; Search for: Ma, Hong; Search for: Estelle, Mark |
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| Affiliation | - National Research Council of Canada. NRC Plant Biotechnology Institute
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| Format | Text, Article |
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| Subject | auxin; TIR1; SCF; ubiquitin-ligase; proteolysis; Arabidopsis |
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| Abstract | The plant hormone auxin regulates diverse aspects of plant growth and development. We report that in Arabidopsis, auxin response is dependent on a ubiquitin-ligase (E3) complex called SCFᵀᴵᴿ¹. The complex consists of proteins related to yeast Skp1p and Cdc53p called ASK and AtCUL1, respectively, as well as the F-box protein TIR1. Mutations in either ASK1 or TIR1result in decreased auxin response. Further, overexpression of TIR1 promotes auxin response suggesting that SCFᵀᴵᴿ¹ is limiting for the response. These results provide new support for a model in which auxin action depends on the regulated proteolysis of repressor proteins. |
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| Publication date | 1999 |
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| Publisher | Cold Spring Harbor Press |
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| In | |
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| Peer reviewed | Yes |
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| NPARC number | 13053137 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 15c5f585-c84c-4738-bc1d-a7a3a7ec81b9 |
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| Record created | 2009-11-25 |
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| Record modified | 2022-09-21 |
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