| DOI | Resolve DOI: https://doi.org/10.1117/12.875471 |
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| Author | Search for: Janz, S.1; Search for: Densmore, A.1; Search for: Xu, D.-X.1; Search for: Cheben, P.1ORCID identifier: https://orcid.org/0000-0003-4232-9130; Search for: Ma, R.1; Search for: Schmid, J.H.1; Search for: Delâge, A.1; Search for: Vachon, M.1; Search for: Lapointe, J.1; Search for: Sabourin, N.1; Search for: Sinclair, W.1; Search for: Li, Y.1; Search for: Mischki, T.2; Search for: Lopinski, G.3; Search for: Mackenzie, R.4; Search for: Liu, Q.4; Search for: Post, E.1; Search for: Lamontagne, B.1; Search for: Halir, R.; Search for: Molina-Fernandez, I. |
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| Affiliation | - National Research Council of Canada. NRC Institute for Microstructural Sciences
- National Research Council of Canada. NRC Steacie Institute for Molecular Sciences
- National Research Council of Canada. Measurement Science and Standards
- National Research Council of Canada. Human Health Therapeutics
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| Format | Text, Article |
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| Conference | SPIE BiOS, January 22-23, 2011, San Francisco, CA, USA |
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| Subject | affinity binding; label-free sensors; photonic wires; ring resonators; silicon photonics; biosensors; fluidics; instruments; nanosensors; optical resonators; optical waveguides; photonic devices; sensor arrays; waveguides; wire |
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| Abstract | We are developing a photonic wire evanescent field (PWEF) sensor chip using 260 nm x 450 nm cross-section silicon photonic wire waveguides. The waveguide mode is strongly localized near the silicon surface, so that light interacts strongly with molecules bound to the waveguide surface. The millimeter long sensor waveguides can be folded into tight spiral structures less than 200 micrometers in diameter, which can be arrayed at densities up to ten or more independent sensors per square millimeter. The long propagation length in each sensor element gives a response to molecular binding much better than currently available tools for label-free molecular sensing. Cost of instrumentation, cost per measurement, ease-of-use, and the number of sensors that can be simultaneously monitored on a sensor array chip are equally important in determining whether an instrument is practical for the end user and hence commercially viable. The objective of our recent work on PWEF sensor array chips and the associated instrumentation is to address all of these issues. This conference paper reviews our ongoing work on the photonic wire sensor chip design and layout, on-chip integrated fluidics, optical coupling, and chip interrogation using arrays of grating couplers formed using sub-wavelength patterned structures. © 2011 Copyright Society of Photo-Optical Instrumentation Engineers (SPIE). |
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| Publication date | 2011 |
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| Publisher | SPIE |
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| In | |
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| Series | |
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| Language | English |
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| Peer reviewed | Yes |
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| NPARC number | 21271759 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 08e3d582-2590-4036-b0b3-f748044249bb |
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| Record created | 2014-03-24 |
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| Record modified | 2020-04-21 |
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